Don’t Deploy Exchange Server 2016 on Windows Server 2016 For Now Due to Stability Issues

Since the release of Cumulative 3 (CU3), which added support for installing Exchange 2016 onto Windows Server 2016 servers, there’s been a series of reports in support forums and blog comments about errors that customers are seeing.

Now has acknowledged that there is in fact a known issue, and there is no current workaround for it.

If you attempt to run Microsoft CU3 on 2016, you will experience errors in the IIS host process W3WP.exe. There is no workaround at this time. You should postpone of CU3 on Windows Server 2016 until a supported fix is available.

That’s all the detail that has been publicly released by Microsoft at this time, but the guidance is clear. You should Exchange 2016 only on Windows Server R2 until further notice.

Source: https://exchangeserverpro.com/dont-deploy-exchange-server-2016-windows-server-2016-now-due-stability-issues/