Hyper-V R2 NLB Error: the interface is mis configured

The Microsoft’s current documentation you’ll still need to shutdown your guest OS. First up, unless your Guest OS is also R2, you’ll need to install the hotfix noted above. However, rather than having to note the cluster’s MAC address, you’ll simply need to change the Hyper-V guest settings to enable MAC Spoofing on the NIC which you configured for NLB: